
王红波,男,教授,博士,高级工程师,执业药师,山东省临沂市人。山东医学高等专科学校药学系副主任。主要研究方向为活性天然药物的结构修饰,拥有发明专利4项。主要承担《无机化学》、《分析化学》等课程教学工作。主持或参与教科研课题近10项,发表论文10余篇,参与编写国家规划教材10部,其中主编1部,副主编4部。
[教育、工作简历]
1997.09—2001.07 山东师范大学化学教育专业,本科;
2001.09—2006.07 中国科学技术大学有机化学专业,博士研究生;
2006.09—2016.07 鲁南制药集团股份有限公司科研部,项目经理;
2016.09—至今 山东医学高等专科学校药学系化学教研室,教师;
2022.06—至今 山东医学高等专科学校药学系副主任。
[发表的论文]
1. Hong-Bo Wang, Bao-Chang Zhai, Wen-Jian Tang, et al.
PhotosensitizedZ-Eisomerization of cinnamate by covalently linked 2-(3΄,4΄-Dimethoxybenzoyl)benzyl moiety via triplet-triplet energy transfer。
Chemical Physics, 333 (2007), 229-235.
2. Qin-Hua Song, Hong-Bo Wang, Xi-Bo Li, et al.
Notable Substituent and Temperature Effects on the Regioselectivity and the Efficiency in Paternò-Büchi Reaction of 4,4’-Disubstituted Benzophenones with 1,3-Dimethyluracil and 1,3-Dimethylthymine。
Journal of Photochemistry and Photobiology A: Chemistry, 183 (2006), 198-204.
3. Wang Hong-Bo, Tang Wen-Jian, Yu Jing-Yu, et al.
Acridin-9-ylmethoxycarbonyl (Amoc): A New Photochemically Removable Protecting Group for Alcohols。
Chinese Journal of Chemistry, 2006, 24, 1465-1468.
4. Wen-Jian Tang, Qin-Hua Song, Hong-Bo Wang, et al.
Efficient photosensitized splitting of the thymine dimer/thymine oxetane adduct modifying cyclodextrin by the binding chromophore。
Organic & Biomolecular Chemistry, 2006, 4, 2575-2580.
5. Jing-yu Yu, Wen-Jian Tang, Hong-Bo Wang, et al.
Anthraquinon-2-ylethyl-1′,2′-diol (Aqe-diol) as a new photolabile protecting group for aldehydes and ketones。
Journal of Photochemistry & Photobiology, A: Chemistry, 185(2007), 101-105.
6. 王红波,杨银萍,赵桂芳等。醋酸阿比特龙的合成,
中国医药工业杂志,2012,43(10):804-806。
7. 杨银萍,王红波。利伐沙班的合成工艺改进,
中国药物化学杂志,2013,23(1):26-29。
8. Hongbo Wang, Jiawei Zuo, Liang Zha, et al.
Design and synthesis of novel glycyrrhetin ureas as anti-inflammatory agents for the treatment of acute kidney injury.
Bioorganic Chemistry,2021,110:104755.
9. Hongbo Wang, Xiaoming Wu, Ziyun Li,et al.
Novel Glycyrrhetin Ureas Possessing 2‑Hydroxy-3-enone A Ring: Modification, Anti-inflammatory Activity, and Targeted STING for the Remedy of Acute Kidney Injury.
ACS Omega 2024, 9: 48821-48834.
[主持、参与的研究课题]
1. 甘草酸衍生物的设计、合成及抗炎作用机制研究,临沂市科技发展计划,2021.1~2022.12。
2. 低毒、高效抗炎活性的甘草次酸衍生物的合成与作用机制研究,山东省医药卫生科技发展计划,2022.3~2024.2。